Urticaria pigmentosa
Urticaria pigmentosa ແມ່ນຮູບແບບທົ່ວໄປທີ່ສຸດຂອງ mastocytosis cutaneous. ມັນເປັນພະຍາດທີ່ຫາຍາກທີ່ເກີດຈາກຈໍານວນຈຸລັງ mast ຫຼາຍເກີນໄປໃນຜິວຫນັງ, ທີ່ເຮັດໃຫ້ເກີດອາການຄັນ ຫຼື ບາດແຜຕາມຜິວຫນັງໃນເວລາທີ່ລະຄາຍເຄືອງ. ມັກຈະເຫັນຈຸດສີແດງ ຫຼື ສີນ້ຳຕານຢູ່ຕາມຜິວໜັງ, ໂດຍທົ່ວໄປແລ້ວບໍລິເວນໜ້າເອິກ, ໜ້າຜາກ ແລະ ຫຼັງ. ��ຸລັງ mast ເຫຼົ່ານີ້, ເມື່ອລະຄາຍເຄືອງ (ເຊັ່ນ: ການຖູຜິວຫນັງ, ການສໍາຜັດກັບຄວາມຮ້ອນ), ຜະລິດ histamine ຫຼາຍເກີນໄປ, ເຮັດໃຫ້ເກີດອາການແພ້ທີ່ສ້າງຂຶ້ນຈາກການລະຄາຍເຄືອງ, ບາງຄັ້ງເອີ້ນວ່າ “ອາການຂອງ Darier”.
☆ AI Dermatology — Free Service
ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
ໃນປີ 2022 Stiftung Warentest ຜົນໄດ້ຮັບຈາກເຢຍລະມັນ, ຄວາມພໍໃຈຂອງຜູ້ບໍລິໂພກກັບ ModelDerm ແມ່ນຕໍ່າກວ່າການປຶກສາຫາລືທາງດ້ານການປິ່ນປົວທາງໂທລະສັບເລັກນ້ອຍເທົ່ານັ້ນ.
relevance score : -100.0%
ReferencesMastocytosis ແມ່ນສະພາບທີ່ມີຈຸລັງ mast ເກີນ, ມັກຈະເພີດໃຈໃນພາກຕ່າງໆຂອງຮ່າງກາຍ ເຊັ່ນ ຜິວຫນັງ, ໄຂກະດູກ, ແລະລະບົດຍ່ອຍອາຫານ. ອີງຕາມອົງການອະນາໄມໂລກ (WHO), cutaneous mastocytosis ສາມາດແບ່ງແຍກເປັນສາມປະເພດຕົ້ນຕໍ. - ປະເພດທຳອິດ (mastocytomas) ປະກອບດ້ວຍ lesions ��ຈຳນວນນ້ອຍ (≤3). - ປະເພດທີສອງ (urticaria pigmentosa) ປະກອບດ້ວຍ lesions ຫຼາຍ, ປົກກະຕິຈຳນວນລະຫວ່າງ 10 ຫາ 100 ຕົວ. - ປະເພດສຸດທ້າຍ ສະແດງການມີການຕິດຕໍ່ຢ່າງກວ້າງຂວາງໃນຜິວຫນັງທັງໝົດ. Urticaria pigmentosa ແມ່ນຮູບແບບທີ່ພົບເລິກທີ່ສຸດຂອງ cutaneous mastocytosis ໃນເດັກນ້ອຍ, ແຕ່ກໍ່ສາມາດເກີດໃນຜູ້ໃຫຍ່ໄດ້. ປົກກະຕິແລ້ວ, ມັນເປັນສະພາບທີ່ບໍ່ເປັນອັນຕະລາຍ ແລະມັກຈະປັບປຸງໃນໄລຍະໂຕ່. ຕໍ່ກັບ mastocytosis ຜູ້ໃຫຍ່, urticaria pigmentosa ບໍ່ຄ່ອຍມີຜົນກະທົບຕໍ່ອະໄວຍະວະພາຍໃນ. ລັກສະນະທີ່ໂດດເດັ່ນອັນໜຶ່ງຂອງ urticaria pigmentosa ແມ່ນແນວໂນ້ມທີ່ສາມາດເຮັດໃຫ້ເກີດຈຸດນ້ອຍ, ອາການຄັນ, ສີນ້ຳຕານແດງ, ຫຼືສີນ້ຳຕານອອກເຫຼືອງ, ຫຼືການປ່ອຍບາດທີ່ຜິວໜັງ, ເຊິ່ງຖືກເອີ້ນວ່າລົມ. ຈຸດເຫຼົ່ານີ້ມັກຈະເກີດໃນໄວເດັກ ແລະອາດຢູ່ຕະຫຼອດຊີວິດ.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
Mastocytosis is a disorder characterized by mast cell accumulation, commonly in the skin, bone marrow, gastrointestinal (GI) tract, liver, spleen, and lymphatic tissues. The World Health Organization (WHO) divides cutaneous mastocytosis into 3 main presentations. The first has solitary or few (≤3) lesions called mastocytomas. The second, urticaria pigmentosa (UP), involves multiple lesions ranging from >10 to <100 lesions. The last presentation involves diffuse cutaneous involvement. UP is the most common cutaneous mastocytosis in children, but it can form in adults as well. It is considered a benign, self-resolving condition that often remits in adolescence. Unlike adult forms of mastocytosis, there is rarely any internal organ involvement in UP. What makes UP particularly distinctive is its tendency to manifest as small, itchy, reddish-brown, or yellowish-brown spots or lesions on the skin, commonly referred to as urticaria or hives. These spots typically appear in childhood and can persist throughout a person's life.
ເດັກນ້ອຍອາຍຸ 6 ປີ ມີອາການສີດຳຫຼາຍຈຸດ ປະກົດຂຶ້ນເທິງໜັງຫົວ ແລະ ��າກນັ້ນແຜ່ລາມໄປທົ່ວໃບໜ້າ ແລະ ຜິວໜັງ ໃນໄລຍະ 6 ເດືອນຜ່ານມາ. ນາງໄດ້ກ່າວວ່າ ອາການລຸກຂຶ້ນ, ປ່ຽນເປັນສີແດງ, ແລະ ມີອາການຄັນເມື່ອມີຄວາມກົດດັນ. ນາງບໍ່ມີອາການຖອກທ້ອງ, ຮາກ, ຖອກທ້ອງ, ຫຼື ຫາຍໃຈຝືດ, ແລະ ບໍ່ໄດ້ສະແດງປະຫວັດການແພດສ່ວນຕົວ ຫຼື ຂໍ້ຄຶດທີ່ກ່ຽວຂ້ອງຈາກຄອບຄົວ. ຜ່ານການກວດສອບ, ພວກເຮົາພົບຈຸດດ່າງດຳຫຼາຍຈຸດຢູ່ໜັງຫົວ, ໜ້າຜາກ, ໃບໜ້າ ແລະ ຄໍ, ພ້ອມກັບຈຸດດ່າງດຳຂຶ້ນຢູ່ໜ້າເອິກ ແລະ ຫລັງ. ທາເບົາໆ ທາຈຸດທີ່ມີອາການບວມ ແລະ ຄັນພາຍໃນ 2 ນາທີ, ແຕ່ອາການຈາງລົງພາຍໃນ 15–20 ນາທີ (Darier's sign).
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
A 6-year-old female, presented with multiple dark-colored lesions, which started over the scalp and further progressed to involve the face and trunk since past six months. She gave a history of elevation, redness, and itching on the lesions on application of pressure. There was no associated flushing, vomiting, diarrhoea, or wheeze. The personal and family history was not contributory. On examination, there were multiple hyperpigmented macules over the scalp, forehead, face, and neck in addition to minimally elevated hyperpigmented plaques over the chest and the back. Gentle rubbing of the lesions elicited urtication and itching within 2 min and it resolved within 15–20 minutes, suggestive of the Darier's sign.
